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The brand physician should consider contacting a poison control center ( or www. Growth (Height brand And Weight) Decreased brand appetite and weight loss have brand been observed in association with the use of ssris and snris. Your family or other caregivers should also be alert to cymbalta changes in your mood or symptoms. Table 2: Treatment-Emergent Adverse Reactions: Incidence of 5 or More and Greater than Placebo in Placebo-Controlled Trials of Approved Indicationsa Adverse Reaction Percentage of Patients Reporting Reaction cymbalta (N8100) Placebo (N5655) Nauseac 23 8 Headache. Cardiac Disorders Frequent: palpitations ; Infrequent: myocardial infarction and tachycardia. FM-1 and FM-2 enrolled a total of 874 patients of whom 541 (62) completed the studies. While gradually reducing brand the dose sounds like a reasonable approach, there is one very big problem. Hepatic Impairment Avoid use in patients with chronic liver disease or cirrhosis see dosage AND administration, Hepatotoxicity, and Use In Specific Populations. Pediatric Use Generalized Anxiety Disorder In pediatric patients aged 7 to 17 years, efficacy was demonstrated in one 10week, placebo-controlled trial. The recommended dose range is 30 to 60 mg once daily. Seek emergency medical attention or call the Poison Help line. Consequently, physicians should carefully evaluate patients for a history of drug abuse and follow such patients closely, observing them for signs of misuse or abuse of cymbalta (e.g., development of tolerance, incrementation of dose, drug-seeking behavior). Common adverse name reactions reported as a reason for discontinuation and considered to be drug-related (as defined above) included nausea (cymbalta.3, placebo.4 and dizziness (cymbalta.3, placebo.4). At steady state, the concentration of cymbalta in breast milk was approximately 25 that of maternal plasma. What happens if cymbalta cymbalta I overdose? Serotonin Syndrome brand The development of a potentially life-threatening serotonin syndrome has been reported with snris and ssris, including cymbalta, alone but particularly with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, and. Chronic Low Back Pain Approximately.5 (99/600) of the patients who received cymbalta in 13-week, placebo-controlled trials for clbp discontinued treatment due to an adverse reaction, compared with.3 (28/441) for placebo. Important information, do not take Cymbalta within 5 days before or 14 days after you have used a MAO inhibitor, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine, or methylene blue injection. Call your doctor at once if you have: a light-headed feeling, like you might pass out; vision changes, eye pain or swelling, eye redness; easy bruising, unusual bleeding; painful or difficult urination; a seizure; a manic episode -racing thoughts, increased energy. Store Cymbalta at room temperature between 68F to 77F (20C to 25C). Warnings Precautions warnings Included as part of the "precautions" brand Section precautions - Suicidal Thoughts And Behaviors In Children, Adolescents, And Young Adults Patients with major depressive disorder (MDD both adult and pediatric, may experience worsening of their depression and/or the. Cymbalta is used to treat name major depressive disorder in adults. Effect On Blood Pressure brand In adult placebo-controlled clinical trials across brand indications from baseline to endpoint, cymbalta treatment was associated with mean increases.5 mm Hg in systolic blood pressure and.8 mm Hg in diastolic blood pressure. This includes aspirin, ibuprofen (Advil, Motrin naproxen (Aleve name celecoxib (Celebrex diclofenac, indomethacin, meloxicam, and others. Pain reduction was observed in patients both with and without brand comorbid MDD. Most Common Adult Adverse Reactions Pooled Trials For All Approved Indications The most commonly observed adverse reactions in cymbalta-treated patients (incidence of at least 5 and at least twice the incidence in placebo patients) name were nausea, dry mouth, somnolence, constipation, cymbalta decreased appetite, and hyperhidrosis. Active ingredient: duloxetine hydrochloride Inactive ingredients: FD C Blue. Reactions are categorized by body system according to the following definitions: frequent adverse reactions are those occurring in at least 1/100 patients; infrequent adverse reactions are those occurring in 1/100 to 1/1000 patients; rare reactions are those occurring in fewer than 1/1000 patients. Cymbalta may increase the risk for suicidal thoughts or behaviors if you are 24 years old or younger. Chronic Musculoskeletal Pain cymbalta is indicated for the management of chronic musculoskeletal pain. For both studies, efficacy analyses were conducted using 13-week data from the combined cymbalta 60 mg and 120 mg once daily treatment groups compared to the placebo group. Instruct patients, their families, and their caregivers to read the Medication Guide before starting cymbalta and each time their prescription is renewed, and assist them in understanding its contents. Major Depressive Disorder The efficacy of cymbalta as a treatment for depression was established in 4 randomized, double-blind, placebo-controlled, fixed-dose studies in adult outpatients (18 to 83 years) meeting DSM-IV criteria for major depression. Cymbalta can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. The stated frequencies of adverse reactions represent the proportion of individuals who experienced, at least once, a treatment-emergent adverse reaction of the type listed.

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