Robin Mesnage

Nicolas Defarge

Louis-Marie Rocque

Joël Spiroux de Vendômois

Gilles-Eric Séralini


Published: July 2, 2015

DOI: 10.1371/journal.pone.0128429



The quality of diets in rodent feeding trials is crucial. We describe the contamination with environmental pollutants of 13 laboratory rodent diets from 5 continents. Measurements were performed using accredited methodologies. All diets were contaminated with pesticides (1-6 out of 262 measured), heavy metals (2-3 out of 4, mostly lead and cadmium), PCDD/Fs (1-13 out of 17) and PCBs (5-15 out of 18). Out of 22 GMOs tested for, Roundup-tolerant GMOs were the most frequently detected, constituting up to 48% of the diet. The main pesticide detected was Roundup, with residues of glyphosate and AMPA in 9 of the 13 diets, up to 370 ppb. The levels correlated with the amount of Roundup-tolerant GMOs. Toxic effects of these pollutants on liver, neurodevelopment, and reproduction are documented. The sum of the hazard quotients of the pollutants in the diets (an estimator of risk with a threshold of 1) varied from 15.8 to 40.5. Thus the chronic consumption of these diets can be considered at risk. Efforts toward safer diets will improve the reliability of toxicity tests in biomedical research and regulatory toxicology.


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4 Responses to “BREAKING: Worldwide Seralini Study Published! Laboratory Rodent Diets Contain Glyphosate”

  1. Diana K. says:

    Thanks for posting this article, Barbara. How interesting. How disturbing. Essentially, what this report shows us is that the toxicology studies (investigating any number of industrial chemicals, pharmaceuticals, vaccines, GMO patented materials, etc.) of the past few decades are skewed due to the conventional mouse subjects’ immune systems being compromised because of their and their ancestor’s conventional–chemically-contaminated–diets (conventional mouse food AND contaminated drinking water) and their resulting DNA damage.

    When does it all stop? In this the best of all possible worlds?

  2. Abe says:

    Sooooo……. What next……. Any Ideas? Well I have a few, but I’m not dumb enough to print it here.

    As Ye Sow, So Shall Ye Reap

    An analysis of dozens of common chemicals that are considered safe in low doses suggests that some may increase cancer risk when combined.

  3. Great news! Hopefully the board of PLOS will not be infiltrated with Monsanto & biotech enthusiasts as Elsevier’s “Food and Chemical Toxicology” was where Seralini’s study was first published. May science remain untethered to corporate interest and remain objective. May it serve mankind.

  4. Alan Donelson says:


    I shall pursue.